Adonis, a revenue cycle management AI orchestration platform, has obtained a $40 million Series C funding round led by Quadrille Capital, with existing investors General Catalyst and Bling Capital also participating. With this newest investment, the company has raised over $95 million since its establishment in 2022. The funding rounds came after a strong performance year for the company, which saw a quadrupling of the revenue in 2025 and net retention exceeding 130%.
The healthcare industry is facing the increasing burden of a pipeline of policy changes and reimbursement complexities, while at the same time, their operations are being constrained. The recent changes in Medicaid and ACA subsidies regulation have led to an increase in uninsured and self-pay patients, while at the same time there is a rise in denial rates and changing payer requirements that are further causing the revenue cycle teams pressure.
To help healthcare organizations cope with the direct and indirect impact of these changes, Adonis has an AI-driven platform that is able to monitor the revenue cycle workflows continuously, detect disruptions, suggest actions, and even move the claims independently for resolution by using a combination of deep learning, AI bots, and decision making algorithms, leading to financial improvement, operational efficiency, and the proper handling of the increasing complexity of the reimbursement process.
“Mount Sinai Health System, like many leading health systems across the country, continues to navigate an increasingly complex revenue cycle landscape, marked by evolving payer policies, rising denial rates, and ongoing workforce constraints. In this challenging environment, Adonis has emerged as a transformative partner,” said Salonia Brown, System Vice President of RCM, Mount Sinai Health System. “With Adonis’ AI-driven platform, we’ve reimagined how revenue cycle operations are executed. By intelligently identifying and prioritizing critical exceptions, Adonis unlocks meaningful financial value and empowers our team to focus on the highest-impact opportunities. Adonis is setting a new standard for how health systems operate, and we believe this is just the beginning of a fundamentally different future for RCM.”
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“The pressure on healthcare organizations is only intensifying,” said Akash Magoon, Co-Founder and CEO of Adonis. “This funding signals that investors are backing solutions that address the structural problems holding RCM teams back, including RCM workforce shortages, denials, and underpayments. Our mission has always been to restore sanity to RCM, and this investment allows us to accelerate the technology RCM teams need to solve these challenges autonomously and at scale.”
“Revenue cycle performance has become a mission-critical driver of financial stability for healthcare organizations,” said Amine Baji, Partner at Quadrille Capital. “As AI adoption in healthcare accelerates, Adonis‘ differentiated platform tackles the most complex workflows end-to-end, from root cause identification through resolution. We look forward to partnering with the Adonis team to accelerate growth and build the leading AI-native orchestration platform for RCM.”
This Series C funding round is a strong indication that the healthcare sector as a whole is increasingly recognizing that revenue cycle optimization is not only a good idea but a necessity for financial stability. Actually, most traditional tools and methods are not only inflexible but also lack the kind of intelligence that is required today to operate in the environment of the constantly changing reimbursement landscape. Adonis, by contrast, with AI solutions that have been trained on billions of claims, helps organizations both to increase their collections, and to reduce the rework that can be very costly, even at the same time, that it reduces the stress and strain on healthcare professionals who are already stretched very thin.
Besides, the human-in-the-loop nature of the platform is such that healthcare leaders can still be very much hands-on and retain a high-level of oversight and control, and that effectively translates to the needed governance that makes the adoption of AI-driven solutions comfortable and with confidence.
Before this funding round, Adonis had already raised over $54 million from such investors as General Catalyst, Point72 Ventures, and the like. With the infusion of this new funding, the firm intends not only to speed up the development of its Intelligence, AI Agents, and orchestration abilities but also to broaden its shares of the industry within health systems, and to hire more staff members at its New York City office to handle the increasing demand.
